Capabilities

Our laboratory capabilities complement those of pharmaceutical chemistry, compound managment, and assay groups and CROs. We work with post-chemistry material and produce reliably pure and well-characterized assay quality material. We specialize in working with high-value compounds where attention to detail and preservation of the sample are critical to the success of late discovery programs.

Post-Chemistry Services:
Final purification
Difficult or unique separations
Chiral separations
Scales from 5 mg to 500 g
Salt exchange
Solvent removal

Compound Management Support:
Aliquoting
Custom labeling, barcoding
Characterization, analysis
Water and residual solvent analysis
Optical purity, EE
Certificate of analysis, QC
Consultation with project team and downstream CROs

Compound Integrity:
HPLC, SFC, SFCMS, LCMS, NMR
Absolute configuration by VCD
Method development
Preliminary stability

Free Chiral Screening: contact us regarding free, rapid chiral screening for feasibility or exploratory studies.


 


 

 

Case Studies
Case 1 - Chiral resolution of an unstable compound
Case 2 - Isolation of a batch API impurity
Case 3 - Removal of a drug canidate regioisomer

eNewsletter
Each month we publish industry insights, purification tips, and case studies involving drug discovery solutions. We also offer special discounts on select chiral chromatography columns to our subscribers. 


 


 

 
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