Mass Balance – What, When, How?

This “fishbone diagram”, shown by permission from Steven Baertschi (S. W. Baertschi et al, Trends in Analytical Chemistry 49 (2013)… Read more

What Type of Chemist Are You?

Have you ever noticed there isn’t a personality chart for chemists?  There are plenty of chemistry roles in drug development,… Read more

EPSA: A New Bioavailability / Permeability Assay

Predictive assays or calculations are established approaches to understanding a drug’s potential bioavailability.  A key physical property to understanding this… Read more

5 Keys to Fast Impurity Isolation

Sometimes you know a lot about the genesis of pharmaceutical impurities, and in some cases you know very little.  In… Read more

Chiral Chromatography and your Distomer

If you’re a discovery chemist using chiral chromatography to resolve a racemate for the first time, you don’t know which of the… Read more