Good friend Joe Helble at Infinity Pharmaceuticals published a nice article entitled “Fast LC for Conventional HPLC Systems” in the April 2011 issue of LC-GC magazine. It’s not a hot topic these days – with UHPLC the fast analytical technique of choice – but from my point of view there are a lot of practical reasons to work with conventional HPLC systems to improve fast analysis.
Joe gives some great examples, but here’s one from my perspective – it’s easier to scale a conventional separation up to preparative LC.
For a link to the article click here.