Chiral Separation

In Averica, we develop scalable processes to meet your needs.

Small or Large Scale Chiral Separation

We deliver finished compounds at scales from milligrams to kilograms. Often we process smaller samples in a few days, and the processes we develop are scalable as your program needs escalate.

Highly pure or isomerically pure test samples of drugs in development not only guarantee more reliable results but are also absolutely required for certain types of testing – toxicity, for example. Waiting for a scalable chemistry process to deliver high-purity materials and chiral purity can delay a program. Our chromatography processes provide qualified compounds fast.

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The Averica Advantage

Fast and Easy To Scale-Up

Averica’s chromatography systems contain custom innovations, delivering the fastest turnaround and highest recovery without sacrificing quality. Upon project completion, clients receive highly pure compounds, an optimized method, and detailed reporting and analytics.

Averica’s depth of experience with HPLC method development and method qualification makes us uniquely suited to provide chromatography methods that result in projects delivered on time and target.

Chromatography Solutions that fit your timeline and budget

Chiral Separation & Evaluation of Enantiomers

  • Chromatography is your best solution for enantiomer supply at the early and intermediate stages of lead candidate profiling.
  • Chiral separation is fast and easy to scale-up, so that you don’t have to worry about compound supply while moving a discovery program toward development.
  • The high efficiency of preparative SFC delivers highly pure compound from milligrams to kilograms.

Chiral Method Development

  • We can develop chiral chromatography methods that are:
  • Scalable for preparative chromatography use
  • Normal phase or SFC for fast analysis and process monitoring
  • Validation-ready for batch release and stability
  • Reversed phase for bioanalysis

Instrument and Detective Systems

  • SFC – Preparative & Analytical
  • HPLC – Preparative & Analytical
  • RP LC – Preparative & Analytical
  • UPC^2
  • UPLC
  • GC
  • ELSD
  • MS
  • CAD Detection
  • PDA/UV
  • NMR
  • Accurate Mass MS

Averica can provide you with dependable and easy-to-implement solutions to help you achieve drug development milestones. Let's talk about how we can make it happen.

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